Fertility decreases with increasing age, and natural pregnancy becomes difficult in most women over 40 years of age. 1,2 Infertility care using assisted reproductive technology (ART) with control ovarian stimulation (COS) supports women who desire pregnancy. 3,4 COS is an exogenous FSH/hMG treatment method to collect a large number of mature oocytes that are used for in vitro fertilization (IVF). 5 However, the number of collected oocytes is limited in some patients who receive COS treatment, and these cases are called "low responders" or "poor responders." Low responders are associated with increasing age, and the ratio of low responders increases