Increasing accumulation of CO2 in the atmosphere mainly caused by fossil fuels combustion of human activities have resulted in adverse global warming. Therefore, searching for treatment methods for effective utilization of CO2 have received a great attention worldwide. Among various methods (e.g., adsorption, absorption, storage, membrane technologies, etc.) have been developed and applied, the sequestration of CO2 using microalgae has recently emerged as an alternatively sustainable approach. In this work, a green microalgal strain Chlorella sorokiniana TH01 was used to investigate its capability in sequestration of CO2 in laboratory scale. Results indicated that the C. sorokiniana TH01 grew well under a wide range of CO2 concentration from 0.04% to 20% with maximum growth was achieved under CO2 aeration of 15%. In a single photobioreactor (PBR) with 10 min empty bed residence time (EBRT), the C. sorokiniana TH01 only achieved CO2 fixation efficiency of 6.33% under continuous aeration of 15% CO2. Increasing number of PBRs to 15 and connected in a sequence enhanced mean CO2 fixation efficiency up to 82.64%. Moreover, the CO2 fixation efficiency was stable in the range of 78.67 to 91.34% in 10 following days of the cultivation. Removal efficiency of NO3--N and PO43--P reached 82.54 – 90.25% and 95.33 – 98.02%, respectively. Our trial data demonstrated that the C. sorokiniana TH01 strain is a promising microalgal for further research in simultaneous CO2 mitigation via CO2 sequestration from flue gas as well as nutrients recycling from wastewaters. Keywords: Carbon dioxide, C. sorokiniana TH01, Photobioreactors, Sequestration, Nutrients removal.

Hợp chất lai của 2-aminobenzothiazole có chứa nhóm 2-aminobenzamide qua cầu nối amide đã được thiết kế, tổng hợp thành công và cấu trúc được xác định bằng các phương pháp phổ cộng hưởng từ hạt nhân (NMR), phổ khối lượng phân giải cao (HRMS). Hợp chất (3) tổng hợp cũng đã được thử hoạt tính kháng tế bào ung thư người in vitro trên hai dòng tế bào A549 và SW480. Kết quả thu được cho thấy, hợp chất (3) không thể hiện hoạt tính đối với dòng tế bào SW480 nhưng lại thể hiện độc tính đối với dòng tế bào A549 với giá trị IC50 là 29.49 µM.

Twelve new compounds including 2-aminobenzamide derivatives bearing benzothiazole and phenylamine moiety were designed and synthesized. The synthesized compounds were tested their cytotoxic activity against A549 and SW480 tumor cell lines. Compounds 3a and 3c exhibited cytotoxicity toward A549 cell line with IC50 values of 24.59 and 29.59 µM, respectively.