Binahong (Anredera cordifolia (Ten.) Stennis) is a plant which comes from Basellaceae family. Also, this plant is also known to have biological activity due to the presence of the bioactive compound. Phenolic acids are bioactive compound and widely used as antioxidants. Identification and testing of antioxidant activity using ethanol extract have been done in this research. Phenolic acids were isolated without hydrolysis (TH fraction), and by acid hydrolysis (fraction HA), and alkaline hydrolysis (HB fraction). Based on the identification using TLC with co-chromatography, UV-Vis and FTIR spectrophotometer, the ethanolic extract of binahong leaves was allegedly suspected contain p-coumaric acid. Based on the results of quantitative analysis using TLC Scanner, it can be seen that the p-coumaric acid content in fractions TH, HA, and HB, 11.4220%; 2.8642%; and 23.3563%, respectively. The result of the antioxidant activity test on ethanol extract was 866.89831 mg / L, while (IC50) value on isolate B was 1263.3333 mg / L.
Hepatoprotector is a liver protected-agent of hepatotoxic. This research was aimed to determine the hepatoprotector effect of ethanol extract of dringo rhizome (Acorus calamus L.) and most effective dose as a hepatoprotector. The study using 20 male rats divided into 5 groups. Group I was given the Na-CMC 1%, group II was given a herbal supplement, and group III, IV, and V were given ethanol extract of the rhizome dringo (Acorus calamus L.) with a dose of 50 mg/100 mg, kgBB/kgBB, and 200 mg/kgBB orally for 7 days. At 5 th day interval 2 hours after administering the test preparations were given a single dose of 2 g of paracetamol/kgBB in all groups except the Group I. Measurement of levels of SGPT is done before and after the treatment the animal test. From the results of a statistical analysis of Kruskal-Wallis' test followed by Man-Whitney's test that dringo Rhizome (Acorus calamus L.) ethanol extracts has the effect of a hepatoprotector in rats. Extract 50 mg/kgBB dose has the same effect as statistically with herbal supplements' group (˃ p 0.05).
Hepatoprotector is a liver protected-agent of hepatotoxic. This research was aimed to determine the hepatoprotector effect of ethanol extract of dringo rhizome (Acorus calamus L.) and most effective dose as a hepatoprotector. The study using 20 male rats divided into 5 groups. Group I was given the Na-CMC 1%, group II was given a herbal supplement, and group III, IV, and V were given ethanol extract of the rhizome dringo (Acorus calamus L.) with a dose of 50 mg/100 mg, kgBB/kgBB, and 200 mg/kgBB orally for 7 days. At 5 th day interval 2 hours after administering the test preparations were given a single dose of 2 g of paracetamol/kgBB in all groups except the Group I. Measurement of levels of SGPT is done before and after the treatment the animal test. From the results of a statistical analysis of Kruskal-Wallis' test followed by Man-Whitney's test that dringo Rhizome (Acorus calamus L.) ethanol extracts has the effect of a hepatoprotector in rats. Extract 50 mg/kgBB dose has the same effect as statistically with herbal supplements' group (˃ p 0.05).
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