Vanadium(V) in the form of NH4V03 or as an aqueous solution of V205 (pH > 9, ammonia solution) has been studied as a modifier for 25 analyte elements of high and moderate volatility. The maximum pre-treatment temperatures ("C) in the presence of 20 pg of V V and 20 pg of VV + 4 pg of Pdll are, respectively: Ag (900 and 1000); Al (1400); As (1450 and 1450); Au (850 and 1000); Bi (850 and 1200); Cd (800 and 800); Co (1100); Cr (1000); Cu (1000and 1150); Fe(1550); Ga (1100and 1350); Ge(900and 1350); Hg(290); In (1100and 1300); Ni (1100); Mn(1000and 1300); P(1500and 1550); Pb(900and 1000); Pd(1400);Sb(1000and 1400);Se(1550and 1400); Sn (1300 and 1400); Te (700 and 1500); TI (1050 and 1100); and Zn (850 and 900). A high efficiency of thermal stabilisation by the mixed modifier V + Pd has been observed for most volatile analytes.Investigations using the modifier have been carried out on slurried and digested biological and environmental reference materials.