Objectives An excessive inflammatory response to SARS-CoV-2 is thought to be a major cause of disease severity in COVID-19. The aim herein was to determine the prognostic value of IL-6, and demonstrate the comparison between IL-6 and related parameters in COVID-19. Methods Data were collected from 115 COVID-19 patients. Results The median age was 46.04 years in the mild group, 56.42 years in the moderate group, and 62.92 years in the severe group (p=0.001). There was a significant difference in the hospitalized clinic to intensive care unit ratio among the patients (p<0.001). The IL-6 values were significantly higher in the severe group than those in the mild (p=0.04) and moderate groups (p=0.043). The area under the receiver operating characteristic curve for IL-6, as predictor of severe clinical condition, was 0.864 (95% CI 0.765–0.963 p=0.000). The longitudinal analyses showed that the severe group presented with significantly increased IL-6 levels during hospitalization. Conclusions IL‐6 seemed to be a guide in the early diagnosis of severe COVID-19 and an ideal marker for monitoring negative outcome.
Background/aim: COVID-19 cases originated in Wuhan and it has become a global problem. The purpose of study to examine the rate of re-hospitalisation within 30 days after the completion of medical treatments for patients suffering from COVID-19. Materials and methods: In this study, the results of COVID-19 patients who were re-admitted to the hospital within 30 days were examined. The general and clinical characteristics of the patients and laboratory results were evaluated using parametric and nonparametric tests. Results: Included in this study were 22 patients, comprising 14 males and 8 females, with re-hospitalisation rate within 30 days and a diagnosis of COVID-19 that was 0.6%. The mean age of the patients who were re-hospitalised was 56.45 years. The major clinical symptoms of the patients who were re-hospitalised, respectively, were cough, shortness of breath, fever. When the levels from the first hospitalisation and the second hospitalisation were compared, an increase in the LYM count and N/L ratio was detected and the difference was statistically significant. Conclusion: A holistic patient assessment and care approach should be adopted by evaluating the symptomatic complaints as well as the comorbidities of the patients, so as to reduce the number of re-hospitalisations.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.