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Food security has a multidimensional nature that has an important and strategic priority in protecting consumers of today and citizens of countries. The application of modern biotechnological methods in food ingredients and food products is evaluated in terms of research and development studies and legal regulations in terms of food consumption and human health. On the other hand, safe food production is important for the detection, management and control of physical, chemical and biological risks that may arise in food. Today, modern biotechnological studies are carried out on transgenic plants, animals and microorganisms for health, safety, economic, cultural and ethical reasons and national, regional and international security in some developed and developing countries. Each country has started to discuss the legal regulations related to the application of modern biotechnology according to its own conditions, especially due to biosecurity concerns. The production of genetically modified foods and control of legal arrangements in Turkey carried out effectively and are continuing to work on this issue.