Introduction: The study aims to determine the main trends in the formation of business centers in Kazakhstan’s two largest cities, Almaty and Nur-Sultan, and to develop the main city planning and architectural recommendations for improving the network of business centers and their maintenance. Materials and Methods: The study’s systemic and complex research methodology allows it to look at business center issues from a variety of perspectives, including economic, socio-political, legislative, urban planning, and innovation. This approach allowed the architecture of business centers to be highlighted as a dynamic, interrelated process that represents the state’s economic power and prestige. Results and Discussion: The identification of trends in the development of business centers as the main type of commercial real estate is intrinsically linked to their natural qualitative growth and structural metamorphoses, transforming future cities into business cities, business parks, business incubators, and eco-towns. Conclusions: The study revealed that a specific feature of the business center is the distinction in its space-planning structure of the recreational and communicative block of premises and rooms into a separate independent functional block, which, both locally and dispersed spatially, carries an ideological and logical practical load and is a functional space for a multi-purpose business building.