A sheet of choroid plexus epithelial cells extends into each cerebral ventricle and secretes signaling factors into the CSF. To evaluate whether differences in the CSF proteome across ventricles arise, in part, from regional differences in choroid plexus gene expression, we defined the transcriptome of lateral ventricle (telencephalic) versus fourth ventricle (hindbrain) choroid plexus. We find that positional identities of mouse, macaque, and human choroid plexi derive from gene expression domains that parallel their axial tissues of origin. We then show that molecular heterogeneity between telencephalic and hindbrain choroid plexi contributes to region-specific, age-dependent protein secretion in vitro. Transcriptome analysis of FACS-purified choroid plexus epithelial cells also predicts their cell-type-specific secretome. Spatial domains with distinct protein expression profiles were observed within each choroid plexus. We propose that regional differences between choroid plexi contribute to dynamic signaling gradients across the mammalian cerebroventricular system.
The mean total number of fibres in each sample was 256 ± 12.3. The results showed that the sizes of the three types of fibres were not modified with the use of FES; the number of type IIa fibres increased in a significant fashion, after using of FES.
Energy expenditure showed a correlation with the angle of thoracic kyphosis. Patients with or without osteoporosis showed the same energy expenditure during the walking period. The SF-36 score was similar for the three groups.
A eletromiografia tem se mostrado um método eficaz no auxilio de diagnósticos e tratamentos de desordens musculares. Na odontologia sua principal aplicação é no tratamento das Disfunções Temporomandibulares. Os profissionais de odontologia não utilizam esta técnica por desconhecerem seus benefícios ou mesmo não terem conhecimento sobre o assunto. Um dos principais objetivos do tratamento utilizando eletromiografia é mostrar ao paciente o estado atual do músculo analisado e sua evolução durante o tratamento, até chegar a uma função satisfatória.
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