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Running head: Bitter Melon: its composition and health benefitsBitter melon (Momordica charantia L.) has traditionally been used as medicinal foods in many developing countries. It is a tropical fruit claimed to have therapeutic effects due to its content of bioactive compounds. The present review is an attempt to highlight the bitter melon varieties, bioactive composition that linked to its therapeutic effects, especially anti-diabetics, in vitro and in vivo models and understanding the mechanisms of actions of bitter melon that associated with epidemiological evidences. This paper also outlines a proposed processing scheme aiming to fully utilise bitter melon and further add values to this fruit.

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