This study compared inspiratory characteristics of the Novolizer and Turbuhaler. Sixty patients with obstructive lung disease (40 asthmatics, 20 patients with COPD) and without DPI experience were enrolled into this investigator initiated, randomized, cross-over study. Collected data of 56 patients were eligible for analysis. Inspiratory pressure and inspiratory flow through both devices were measured in every patient using a double-beam oscilloscope. Peak inspiratory flow (PIF), duration of inspiratory flow > 60 l/min and increase in inspiratory pressure were significantly higher in the Novolizer group. In addition, the inspiratory flow rate 0.1 s after beginning of inhalation was over two-times higher at inhalation through the Novolizer compared to inhalation through the Turbuhaler. The Turbuhaler data, but not the Novolizer data, showed a significant negative correlation between lung function and inspiratory flow. The dynamic resistance of the Turbuhaler was 5.5-times higher than that of the Novolizer. Patients using the Turbuhaler had to invest a significantly higher inspiratory effort compared to the use of the Novolizer in order to achieve the same inspiratory flow (e.g., 60 l/min). Indeed, more than 40% of the patients in the Turbuhaler group failed to reach an inspiratory flow of 60 l/min. Overall, patients inhaling through the Novolizer had a better inhalation performance than those inhaling through the Turbuhaler.

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ÜBERSICHT nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn n EinleitungBei COPD stellt die physikalische Therapie eine wichtige Ergänzung zur medikamentösen Therapie dar.Physiotherapeutische Maûnahmen sollen das Abhusten von Bronchialschleim verbessern und erleichtern und so die Dyspnoe senken und Infekten vorbeugen.Techniken, die hierzu verwendet werden, sind das ¹Huffingª, das bewusste Husten, tiefes Einatmen, Lagerungen, Vibrationstechniken der Brustwand, ¹Abklopfenª des Thorax sowie Benutzung spezieller Hilfsgeräte wie PEP-Maske bzw. oszillierender PEP-Systeme wie das RC-Cornet oder das VRP1 (Flutter).Weitere physiotherapeutische Maûnahmen haben zum Ziel, den Atemwegskollaps bzw. das ¹Air-trappingª zu vermeiden; diese Techniken werden dann angewendet, wenn die COPD mit zunehmendem Lungenemphysem einhergeht.Physiotherapie mit oszillierenden PEP-Systemen (RC-Cornet , VRP1 ) bei COPD Pneumologie 2000; 54 441Dieses Dokument wurde zum persönlichen Gebrauch heruntergeladen. Vervielfältigung nur mit Zustimmung des Verlages.

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