Medulloepitheliomas are rare congenital tumours arising from the epithelium lining the medullary tube. They are usually detected in the first decade of life. They may be teratoid or non-teratoid. Regional and distant metastases are rare. Extraocular extension of disease appears to be the most important prognostic feature. Surgical resection is the usual mode of treatment. The role of other adjuvant modalities is as yet unclear.
Hypertrophic osteoarthropathy (HOA) is a condition characterized by periosteal reaction of tubular long bones and characteristic bulbous deformity of the digital tips with synovial effusion. It is usually encountered in conjunction with diseases involving the lungs, mediastinum, heart, pleura and gastrointestinal tract. The occurrence of HOA as a paraneoplastic manifestation in nasopharyngeal carcinoma is rare and only a handful of cases have been reported in literature and that too in the pediatric age group. An association with pulmonary metastasis was often described in these case reports. We present a case of HOA associated with nasopharyngeal carcinoma in a 20 years old gentleman in the absence of pulmonary metastasis.
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