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Among the nine oilseed crops grown in India, Sesamum ranks f ifth for important edible oil crop after groundnut, r a p e s e e d-m u s t a r d , s u n f l o w e r a n d s o y b e a n (www.agricoop.nic.in). India accounts for 39 % area, 27 % production and 40 % export of sesame in the world. India holds a top position in the world in sesame-acreage (24 %) and contribution in export (40 %) (Raikwar & Srivastva, 2013; Iqbal ., 2016; http://www.faostat.fao.o7 rg/site/567/default.aspx#ancor). In India, cultivation of the crop is mainly conf ined to the states

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Assam is a state in North-East India which is considered as a biological hotspot. Present communication is the first consolidated updated list of cerambycid fauna of Assam and reports 95 species, 64 genera, 32 tribes and 3 subfamilies. Among the three subfamilies from Assam, subfamily Lamiinae shares 49 species, followed by the subfamily Cerambycinae with 38 species and Prioninae with only 8 species.

Bioactive components of dietary phytochemicals have been reported to possess antitumor activities. Evidences suggested key role of stress responsive p38MAPK in the induction of nutraceuticals mediated apoptosis in hepatocellular carcinoma (HCC). Current study demonstrated detailed molecular bagatelle associated with p38 MAPK mediated effective suppression of cell growth both in HepG2 and chemically induced liver carcinoma after S-allyl cysteine (SAC) treatment. SAC promoted p38MAPK activity responsible for p53 phosphorylation, its stabilization followed by nuclear translocation leading to induction in expression and oligomerization of Fas protein. Distinctive p38MAPK-p53 axis dependent Fas-FasL-FADD mediated caspase activities along with perturbed cell cycling became normalized with continuation of SAC treatment for another month to diethylnitrosamine induced liver carcinoma. Co-treatment with SB203580, the p38MAPK inhibitor, prevented pro-apoptotic effect of SAC by altering p53 phosphorylation and death inducing signaling complex conformation in HepG2 and induced HCC. Collectively study suggested significant contribution of p38MAPK-p53-DISC-Caspase pathway in the regulation of anti-neoplastic activity of SAC against HCC. K E Y W O R D S DEN, Fas, HepG2, p53, pp38MAPK, SAC