Blocking the JNK/c-Jun cell death pathway is a feasible approach to treating oxidative stress-induced apoptosis within the cochlea and may have application as an otoprotective strategy during cochlear implantation.
Trichoblastoma is an uncommon benign cutaneous neoplasm of the hair germ cell. The pigmented variety of the tumor is rare. There have only been a few case reports describing the malignant counterpart of trichoblastoma. There are no reports describing a pigmented variety of malignant trichoblastoma. We are presenting a case report of a 47-year-old patient with malignant trichoblastoma containing melanin deposits and propose to define this variety of the tumor as a separate entity: malignant melanocytic trichoblastoma.
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