The APS Journal Legacy Content is the corpus of 100 years of historical scientific research from the American Physiological Society research journals. This package goes back to the first issue of each of the APS journals including the American Journal of Physiology, first published in 1898. The full text scanned images of the printed pages are easily searchable. Downloads quickly in PDF format.
The accuracy, sensitivity and reproducibility of several isovolumic force-velocity indices of myocardial contractility were compared. Contractile element velocity was calculated using both two-element (total pressure) and three-element (developed pressure) models of cardiac muscle. While all indices demonstrated comparable sensitivity to inotropic state, only Vmax using developed pressure was independent of preload and appeared to be a useful index of the myocardial contractile state.
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