No abstract

Citicoline was safe but ineffective in improving the outcome of patients with acute ischemic stroke as measured by the planned analyses. Post hoc analyses suggest that a modest treatment effect may have been seen if more traditional analyses had been used.

IUSS is a validated patient reported measure of urgency severity for collecting event specific information in the context of a clinical trial.

Background and Purpose-Statins reduce the risk of stroke recurrence, but the benefits of statins in improving outcome of acute stroke patients have not been well explored. Methods-We assessed potential effects of statins initiated before or within 4 weeks of stroke on 90-day outcome.Favorable outcomes were National Institutes of Health Stroke Scale (NIHSS) score Յ2 at 12 weeks and modified Rankin Scale (mRS) Յ2.