Background. Retrospectively evaluation of several patients who had undergone appendectomy in our hospital was carried out which aimed to present the efciency of diagnostic tests and demographic data of cases. Available pathological reports were interpreted for the following parameters: age, gender, and pathological diagnosis. In addition, the demographic information and clinicopathologic characteristics of the subjects with unusual histopathologic ndings were assessed in detail, and re-examination of the available resected appendix specimens was done. Methods Inpatient records of the patients who had been operated for acute appendicitis in the hospital associated with Khaja Bandanawaz University – Faculty of medical Sciences; from January 2018 to November 2022, were retrospectively evaluated. Results Subjects were categorized into 2 groups. Cases with histopathologic examination reported as acute appendicitis constituted group-1, and cases with unusual pathologic ndings other than acute appendicitis constituted group-2. The group-2 consisted of low-grade mucinous neoplasms, mucoceles, carcinoid tumor, granulomatous inammation, intraluminal Enterobius vermicularis, and mesenteric cyst. Conclusion Acute appendicitis is a common surgical emergency condition in the department of General Surgery. Most of the resected specimens of appendectomy revealed typical histopathologic ndings, few showed unusual histopathologic ndings. We suggest routine histopathological examination even if the macroscopic appearance of the specimen is normal.
Background Bone marrow examination is performed by two methods Aspiration and Trephine biopsy. Despite recent advances in eld of molecules hematology and ow cytometry, bone marrow histology remains the corner stone in the diagnosis of acute leukemia. Hence, the present study is taken up to assess the signicance (& complementary roles) of various observations on bone marrow aspiration and trephine biopsy in relation with clinical details and peripheral blood ndings. Methods Retrospective data of leukemic cases whose bone marrow aspiration and Bone marrow biopsy were performed simultaneously were selected ranging from January 2020 to December 2021. Results 30 cases were reviewed retrospectively where bone marrow aspiration and biopsy was done simultaneously. Majority of Patients fall under the age group 31-40 and there was male Predominance. AML was found predominantly followed by CML, of these AML cases most common were of AML M3 type. Out of the 30 cases 22 showed a positive correlation between bone marrow aspiration and bone marrow biopsy; and 26 cases showed concordance on both aspirate and Biopsy. Conclusion Bone marrow evaluation is an important and effective tool in diagnosing and evaluating leukemia
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