The purpose was to determine the effectiveness of endothelial-epithelial dystrophy treatment with subconjunctival injection of low molecular weight hyaluronic acid.Prospective material of 14 corneas with different epithelialepithelial dystrophy forms were examined and treated. To study the morphological features of keratopathy with the background of glaucoma staining of histological preparations with hematoxylin and eosin; histochemical staining (PAS reaction, MSB,Masson,Congored; IHC with CD44, MMP9, TGFβ1 were used.According to the results obtained, in the group of patients with EED, with the background of the use of an injectable form of hyaluronic acid, the activity of inflammation decreases due to a decrease in the epithelial and stromal expression of CD44 and MMP9. The proapoptotic and profibrotic action of TGFβ1 decreases.

No abstract

Aim. To study the association between a positive results of Heart-type fatty acid binding protein (h-FABP) test with the development of adverse outcomes during the year of observation in patients with non-ST elevation acute coronary syndrome (NSTE-ACS) depending on the type 2 diabetes mellitus (DM-2) presence.Material and methods. The study included 153 patients with NSTEACS hospitalized in the department of emergency cardiology in the period from March 2014 to January 2017. In addition to the standard examination, all patients underwent a qualitative analysis on the h-FABP in venous blood. Results. Kaplan–Meier estimator demonstrated a significant probability of a combined end point in patients with positive h-FABP, both with and without DM-2. H-FABP also acts as a marker for the development of adverse outcomes during the year after NSTE-ACS. Patients with adverse outcomes and type 2 diabetes mellitus had the highest frequency (100%) of positive test reactions.Conclusion. H-FABP positive test when admitted to hospital may be considered as a predictor of adverse long-term outcomes in patients with NSTE-ACS. That statistics is most significant for patients with DM-2.

An analysis of changes in the CD44 and MMP9 expression during the keratopathy after corneal inflammatory diseases treatment with injected hyaluronic acid is presented.

The effect of salt mist exposure on the surface structure and permeability of thermoplastic polyurethane used in the production of temporary storage tanks and transportation of diesel fuel was investigated. After exposure to salt mist, the analysis of microphotographs showed the alignment of the surface of the polymer material. IR spectroscopy revealed a change in the chemical composition of thermoplastic polyurethane, and the appearance of a quaternary ammonium salt, which leads to an increase in the polarity of polymer macromolecules and increases the relaxation rate of the polymer material structure. An approach to modeling the natural loss of diesel fuel during storage in elastic tanks is proposed. The model parameters allowed us to quantify the effect of salt mist on the diffusion permeability of thermoplastic polyurethane for diesel fuel. At a storage temperature below 60 °C after exposure to salt mist, the tightness time increases and the natural loss of diesel fuel decreases during storage in the tank.