Present investigation focusing on the post-harvest fungal pathogens, fungal diseases and economic losses of papaya fruits (Carica papaya L.). Matured, ripened and infected fruits of papaya were subjected to isolation of their associated fungal pathogens. Fruit bating method was followed for isolation of fungi from infected papaya fruits. Total 10 fungal genera and 12 species viz. Aspergillus flavus, Alternaria alternata, Alternaria sp., Mucor mucedo, Rhizopus stolonifer, Fusarium thapsinum, Fusarium chlamydosporum, Helminthosporium cassiicola, Colletotrichum gloeosporioides, Penicillium chrysogenum, Psathyrella candolleana and Ascochyta graminicola were reported as post-harvest fungal pathogens of papaya fruits. K e y w o r d sPapaya (Carica papaya L.), Fungal pathogens, Fungal diseases