ChemInform Abstract A mixture of the regio-and stereoisomers of the macrocycle (VII) and its analogues obtained from (V) and (VIII) (instead of (IV)) is used to form a unimolecular ion channel. A large unilamellar vesicle with an imposed pH gradient shows a fast collapse in the presence of (VII). This effect is accelerated when a proton carrier is added.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.