Objective on creating a universal tool with Russian user interface (UI) to systematically collect and store epidemiological-demographic and clinical-laboratory data of patients with the possibility of their structured export for subsequent multifaceted analysis.Materials and methods. When creating an online tool, the solutions of European colleagues used to conduct a multicenter study of EuroSIDA, including a list, algorithms for collecting, storing and exchanging data, were used as a model.Research and discussion. A Russian UI online resource RuSIDA has been developed, hosted on the website http://hivgen.org/, designed to fulfill the tasks above. The tool requires authorized access and has been successfully tested on data collection from HIV-infected patients at several AIDS centers in the Russian Federation.Conclusion. The developed online resource RuSIDA can be used to maintain medical electronic records, intralaboratory databases, as well as to conduct epidemiological monitoring of various nosologies and multicenter scientific studies.