The results of numerical studies of the possibility and efficiency of intra-cavity phase correction of Cr:CdSe laser radiation with the moving active elements using an adaptive optical system without a wavefront sensor are presented. The beam quality of the Cr:CdSe laser directly depends on the speed of movement of the active element due to the influence of thermal effects. The peak radiation power has determined by the efficiency of the resonator and the cooling system of the active element. It has been shown that the using of intra-cavity adaptive correction in the Cr:CdSe laser can significantly reduce the influence of thermal effects and expand the range of laser operation in single-mode regime.