Hypertensive disorders of pregnancy are a leading cause of maternal morbidity and mortality worldwide, accounting for more than 70,000 maternal deaths each year. Of all maternal deaths, 10–15% are directly associated with preeclampsia (PE) and eclampsia. The new version of the Ukrainian National Clinical Guideline and Clinical Protocol «Hypertensive disorders during pregnancy, childbirth and the postpartum period» 2022 presents a synthesis of the scientific evidence that is relevant to the concerning severe PE treatment strategies. It was presented the new algorithm of clinical management for severe pre-eclampsia «CALM DOWN» that implemented to the new Ukrainian clinical protocol of primary, secondary (specialized) and tertiary (highly specialized) medical care. CALM DOWN is the special mnemonic that means «step by step strategy» for the medical teamwork. Conclusions. The algorithm «CALM DOWN» have been proposed for the optimal timing of severe PE, offers to systematize the participation of each member of the team in the provision of emergency care and should be implemented in clinical practice based on the peculiarities of the specifics of work, resources, functioning and localization of the maternity facilities when forming personal route of the patient.