В статье представлены данные по эпидемиологии рака предстательной желе-зы, высокая распространенность и рост заболеваемости обусловливают актуаль-ность исследований по данной онкопатологии. Показано, что увеличение числа впервые выявленных случаев связано в том числе и с программой скринингового обследования мужчин путем определения уровня простатспецифического анти-гена. Освещены современные диагностические методы выявления модифика-ций простатспецифического антигена, обладающие большей чувствительностью и специфичностью в отношении рака предстательной железы. Акцентировано внимание на изменение уровня простатспецифического антигена в зависимости от возраста, что необходимо учитывать при диагностике злокачественных ново-образований предстательной железы. Data on epidemiology of a prostate cancer are presented in article, high prevalence and body height of a case rate cause relevance of researches on this oncopathology. It is shown that the number augmentation for the first time of the taped cases is bound including to the program of a skrining of inspection of men by determination of level of prostates -a specific antigen. Modern diagnostic methods of identification of modifications of prostatesa specific antigen, possessing larger sensitivity and specificity concerning a prostate cancer are lit. The attention to change of level of prostates -a specific antigen depending on age is focused that needs to be considered at diagnostics of malignant neoplasms of a prostate.
This article presents an analysis of literature data of the study of exogenous and endogenous etiologic risk factors for the progression of urolithiasis in elderly and senile patients, the clinical course, modern treatment methods and tactics for managing patients of this age group. It was noted that patients of the older age group require special attention both in the choice of treatment tactics and in further observation due to a decrease in the functional reserves of the renal parenchyma and the presence of concomitant diseases. In the diagnosis and treatment of urolithiasis in elderly patients are preferred to use non-invasive methods. (For citation: Agenosov MP, Kagan OF, Kheyfets VKh. Peculiarities of clinical course of urolithiasis in patients of elderly and senile age. Urologicheskie vedomosti. 2017;7(4):53-59. doi: 10.17816/uroved7453-59).
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