Virtual poster abstractsworth mentioning that more studies are required to evaluate the side effects of Remdesivir during pregnancy. VP31.25The impact of the COVID-19 pandemic on healthcare providers in the labour ward

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Electronic poster abstractsMethods: A total of 657 women with16 weeks -41 weeks of normal gestation were enrolled in the study who received routine obstetric ultrasound in our hospital from September 2008 to March 2015. The volume and blood flow parameters of kidney and fetal growth parameters were measured by two and three dimensional ultrasound. The relations between various parameters of kidney with gestational age, growth indexes were analysed. Results: Renal volume was linearly associated with gestational age, and renal volume = -7.01 + 0.554 × gestational age (16 weeks≤ gestational age≤ 41 weeks).Fetal volume was significantly related to growth indexes, and the correlation with height, weight before pregnancy was not obvious.PSV, EDV and TAMXV of renal artery increased with gestational age; S/D, PI and RI decreased with gestational age. Conclusions: The volume of normal fetal kidney increases gradually along with the gestational age, a linear correlation is between them.The size of normal fetal kidney is associated with fetal growth itself, but is not affected by maternal height, weight before pregnancy. With the increase of gestational age, the blood flow of fetal renal artery speeds, resistance drops and blood flow perfusion increases. Objectives: Evidence suggests that an adverse environment during intrauterine life and early childhood is a risk factor for a wide spectrum of disorders later in life, including cardiovascular and renal disease. We aim to evaluate the role of intrauterine growth restriction in kidney disease in adulthood. Methods: An electronic search was conducted through October 2016 in the CENTRAL, LILACS, MEDLINE, and EMBASE databases. The inclusion criteria were studies comparing renal function in adulthood with birth weight using transversal or longitudinal designs. The reviewers analysed the inclusion criteria and risk bias and extracted data from the included studies. Twenty articles met the inclusion criteria for the systematic review, and 13 were included in the meta-analysis. Results: There was an increased risk of developing end-stage renal disease (risk ratio (RR) 1.31, 95% confidence interval (CI): 1.17, 1.47), a lower glomerular filtration rate (ml/min) (mean difference (MD) -7.14; 95% CI: -12.12, -2.16), microalbuminuria (RR 1.40; 95% CI: 1.28, 1.52) and a small increase in the albumin/creatinine ratio (MD 0.46; 95% CI: 0.03, 0.90) in the low birth weight group. Conclusions: Our results suggest that low birth weight is related to renal dysfunction in adulthood. Objectives: Although an absent or reversed a-wave in ductus venosus (DV-RAV) is reported to be the terminal finding of fetal growth restriction (FGR), we have seen a DV-RAV that disappears in a short span of time, causing us to reconsider the mechanism of DV-RAV in FGR. EP14.08Methods: This was a retrospective study of 499 FGR cases, including 14 with DV-RAV. Transabdominal amnioinfusion (AI) was performed when oligohydramnios was severe and/or a sign of cord compression was detected. DV-RAV that disappeared in a sho...

Conclusions: Real-time VCI-A with a 4D electronic probe is an effective tool for imaging the fetal extremities in mid-trimester examinations and carries some advantages over conventional 2D sonography. Objectives: To assess the development in the diagnosis and outcome of prenatally diagnosed fetuses with talipes equinovarus (TEV). Methods: A retrospective evaluation of diagnosis, management and follow-up of cases of prenatally diagnosed fetuses with TEV in the years [2007][2008][2009][2010][2011][2012][2013][2014][2015][2016]. Results: We diagnosed 114 fetuses with TEV in our centre. The average age of women was 32.4 years. We found the outcome in case of 80 fetuses. There was a total of 48 fetuses with isolated TEV and of that, 32 fetuses were with associated anomalies. None of these malformations have been diagnosed in the first trimester. The diagnosis was set between 16 -32 weeks, with an average of 20.2 weeks. The ratio of male:female representation was 2.4:1. A positive family history of TEV has been present in 24 (30%) cases. Chromosomal aberration was diagnosed in 11 (14%) fetuses, false-positive diagnosis in 8 fetuses (10%). In 42 (75%) children, the conservative treatment has been followed up by surgical treatment, of that in 17 (30%) repeatedly. In the group of 48 fetuses with isolated TEV were diagnosed 29 fetuses with unilateral and 19 with bilateral TEV. One fetus died in utero. 47 children were born alive. In the case of isolated TEV there were postnatally diagnosed neurodevelopmental or structural abnormalities in 6 (13%) children. We diagnosed 32 fetuses with associated anomalies with TEV, with that 81% had the bilateral. In the group with associated congenital defect 22 (27.5%) women terminated the pregnancy. 9 children were born alive. Conclusions: In the case of isolated bilateral TEV, associated anomalies (T18, T21, Becker muscular dystrophy, FRAXA syndrome) were detected using AMC. Prenatally undiagnosed anomalies were VSD, anal atresia, hypotonia, Freeman Sheldon syndrome. AMC was used in case of 85 (75%) fetuses with TEV. Because of the possible associated anomalies, which cannot be diagnosed by ultrasound examination, the invasive procedure should be recommended to patients, especially in the case of bilateral TEV. EP07.10 EP08: FETAL STRUCTURAL ABNORMALITIES IEP08.01 Hemodynamic indices of mother-placenta-fetus system in pregnant at high risk of intrauterine infection L. Vygivska, E. Radzishevskaya, V. Kalnytska Kharkiv National Medical University, Kharkiv, UkraineObjectives: To assess hemodynamic criteria of mother-placenta-fetus system in pregnant at high risk of intrauterine fetal infection (IFI). Methods: The study involved Doppler examination of hemodynamics in mother-placenta-fetus system in 93 pregnant at high risk of IFI development with placental dysfunction. Screening for urogenital infections detected monoinfections in 26.9% and mixed bacterial-viral infections in 73.1% of patients. Blood flow velocity was studied in uterine arteries, umbilical artery and medial cerebral arte...

Two fetuses with associated anomalies proved to be aneuploidic(25%). 2 pregnancies (one with a polymalformed fetus and another one with Down's syndrome) were terminated by abortion. The pregnancy with SUA and Potter syndrome developed anamnios and finished at 31 weeks, followed by neonatal death. The other fetuses with SUA were born at term, with normal karyotype. The anomalies described by US were confirmed after birth. Postpartum we found one case of imperforate anus and one case of bicuspid aortic valve, missed at the US screening. Conclusions: The single umbilical artery is an important finding during morphological ultrasound exam. If it is associated with other US anomalies, the fetal karyotype is mandatory, the risk of fetal aneuploidy being increased. The newborn must be carefully studied, in order to diagnose other anatomical anomalies missed at the prenatal evaluation.