To analyze modern state of application of biological technique of protection of crops in Ukraine and its regions, development of domestic production of biological products in the context of world experience and prospects of application of biomethod, basic trends of development of this market and prospects of ecological farming agriculture. Methods. Analytical, economic-statistical, comparative analysis, graphical and cartographical. Results. In the last years in Ukraine there was a resistant negative trend of dominance of chemical methods of protection of crops above biological. Thus situation in regions is different: if in 2016 the average index of share of biological technique in total amount of application of means of protection of crops across Ukraine was 4,6 %, then in 9 regions this parameter was above and oscillated from 5,0 up to 13,0%; in the majority of regions the share of biomethod did not exceed 1-3%, and in 5 areas had not reached 1%. Regions with the greatest cultivated areas of crops head antiratings on application of biological techniques of protection of crops with the volumes which do not exceed 5% of cultivated areas (Dnipropetrivsk, Zaporizhzhia, Kharkiv, Mykolaiv, Kirovograd, Odesa, Kherson oblasts). Conclusions. In Ukraine application of ecologically safe biological technique of protection of crops tends to the further reduction. For overcoming this situation they offer the most comprehensible scripts: eurointegration-implementation of organic legislation of EU and increasing areas under organic farming up to 1,2%, under ecological-up to 1,6% of all area occupied under farmproduction; national-formation and legal maintenance of organic farming, maintenance of national system of collective safeguard of both organic and ecological farming agriculture and increasing areas under organic farming up to 1,2%, under ecological-up to 5,6% of all areas occupied under farmproduction.

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The problem of industrial production of biological plant protection products in Ukraine is important and relevant. The purpose of this study is to determine the principles of innovative approaches in the production of plant protection products based on microbiological drugs and entomophages and to propose the organizational structure of production of these products in Ukraine. Methods of theoretical generalization, research in applied microbiology and entomology, analysis and synthesis were used. The basic technological and technical methods and equipment for production at enterprises of different levels of biological plant protection products (BZZR) and their application in agrocenoses developed by ITI "Biotechnics" of NAAS are resulted, the general structure of system of biological protection of plants in Ukraine is offered. Emphasis is placed on specific technologies and equipment for the production of microbiological preparations of various scales: bacterial, fungal, viral, the use of nematodes. Attention is paid to the production of entomological drugs to protect plants from pests. Ground methods of BZZR introduction into agrocenoses and with the use of aviation are offered. The proposed innovative approaches to the development, creation and use of OSH in Ukraine, based on the system of bioproduction of these tools, will significantly increase their use in plant protection in organic production and the share of integrated plant protection. The ways of development, creation of industrial production and use of biological plant protection products in Ukraine are considered and offered, based on the developed system of bioproductions of these means. This will significantly increase their use in plant protection in organic production and the share of integrated plant protection.

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