organic chemistry, review organic chemistry, review Z 0200 37 -272 Polycyclic Fluoroquinolinones -[methods of synthesis; 112 refs.]. -(MOKRUSHINA, G. A.; NOSOVA, E. V.; LIPUNOVA, G. N.; CHARUSHIN, V. N.; Russ.

Fused pyridine derivatives R 0450Synthesis and Antiviral Activity of Fluorinated Pyrido[1,2-a]benzimidazoles. -A series of title pyridobenzimidazoles (V), (VI), (VIII) and (X) as well as the corresponding amino derivatives (by transformations at the formyl or chloro substituents) is prepared and tested for their antiviral as well as cytotoxic activity. Only derivatives (VIII) and (X) possess weak activity against ortho-pox viruses. The other derivatives are inactive. -(KOTOVSKAYA, S. K.; BASKAKOVA, Z. M.; CHARUSHIN, V. N.; CHUPAKHIN, O. N.; BELANOV, E. F.; BORMOTOV, N. I.; BALAKHNIN, S. M.; SEROVA, O. A.; Khim.-Farm. Zh. 39 (2005) 11, 12-16; Dep. Chem., Ural State Univ., Ekaterinburg 620083, Russia; Russ., Abstr. Eng.) -Mischke 15-142

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Pyrazine derivatives R 0550New Method for the Anellation of the Pyridine Fragment to Azines. -An intramolecular reaction is used as key step for the anellation of a pyridine ring to quinoxalines leading to compounds of type (III) which are fragments of many highly active antibacterial drugs. -(CHARUSHIN*, V. N.; BOGUSLAVSKY, A. M.; PONIZOVSKY, M. G.; KODESS, M. I.; CHEKHLOV, A. N.; MKOYAN, S. G.; ALDOSHIN, S. M.; Russ.