The study was conducted on 15 dogs aged 1.5-12 years, kept in urban conditions with symptoms of chronic stress caused by various factors: moving to a new place of residence, fear of loneliness, loss of the owner, exhibition career, active breeding activities. The drug Klim Peter was given to all animals for 21 days at a dosage of 1 tablet per 10 kg of live weight 1 time per day. Blood samples were taken for morphological and biochemical studies before the start of the study and after the use of the drug (on the 24th day from the start of the experiment). The drug contributed to a significant reduction in the initially elevated level of white blood cells, the number of red blood cells and the concentration of hemoglobin, a decrease in ESR. The ratio of white blood cells in the leukogram approached the standard values. Protein and albumin levels were significantly increased.The normalization of anabolic processes was confirmed by a decrease in urea and creatinine levels, as well as a significant decrease in the level of bilirubin and the activity of enzymes – ALT, AST and alkaline phosphatase. After 5-10 days after the start of taking the drug, the animals showed normalization of appetite and digestion, after 14-18 days, neurological symptoms were leveled (destructive behavior, tremor, unmotivated aggression, obsessive behavior). By the 20th day, there was an improvement in the condition of the skin and coat, molting in most stopped or decreased, the coat became thick, shiny. Thus, the use of the drug Klim Pet had a positive effect on the clinical condition, and also helped to neutralize the effects of stress factors of various etiologies, had a hepatoprotective effect, optimized the metabolism and activity of the immune and nervous systems, contributed to improving the condition of the fur and skin.

One of the most pathogenic helminth species for the young of the northern fur seal (Callorchinus ursinus) is the nematode (Ancylostomatidae family) Uncinaria lucasi. The ecology of the definitive host determines the adaptation of the parasite to the host, the development of additional transmission mechanisms. The main adaptation of the parasite to the host is the ability of invasive larvae to settle in the tissues of all sex and age groups of the seal herd, which makes it possible to avoid wintering in the ground. At present, the fate of these larvae is unknown, as well as the role of each of the age groups of seals in the implementation of the life cycle of this helminthiasis, in connection with which the purpose of the work was to determine the role of the sex and age groups of the seal herd to maintain the hostparasitic system of the seal – uncinaria. The study found that female northern fur seals are a mandatory link in the life cycle of U. lucasi and they should be considered as.

One of the global environmental problems facing man is the pollution of the oceans by industrial and household garbage. Several hundred seals and sea lions injured by foreign objects are registered annually in reproductive rookeries. Without timely release, these animals are doomed to perish. In this regard, the purpose of the work was to test the technique of freeing injured marine mammals from foreign objects of anthropogenic origin using methods of remote sedation of animals. The problem of implementing measures for the release of marine mammals is associated, among other things, with the lack of proven methods and dosages of sedatives for these animals.In the course of this study, it was revealed that in order to carry out remote sedation, the following factors must be taken into account: weather conditions, distance to water, the presence of other animals between the object and the water, terrain features, danger from other animals, the place of the shot, the dose. The choice of an animal must be carried out depending on the period (harem / post-harem), age, psychological state, body weight and physical condition. In the course of working out the technique of freeing injured marine mammals from foreign objects of anthropogenic origin using methods of remote sedation of animals in a natural habitat, an algorithm for remote sedation using a Bushnell HOLO sight daninject 2528 mod jm remote injector was developed and tested (barrel diameter 11 mm, pressure in the applicator chamber 5 Bar (500 kPa), the size of the syringe-dart for sedation CMC 2-3 ml, needle length 4 cm), a scheme of combined anesthesia with the help of zoletil 100 (telazol) and medin (medetomedin) 1% has also been developed and successfully tested.

Intensive use of radioactive isotopes in industry, abnormal emissions of nuclear fission products into the environment gradually increase the level of natural background radiation. As a result, there is a problem of farming, the main producer of food for the population, raw materials for industry, associated with the control of the level of contamination of soil, water, and livestock products. It is necessary to constantly monitor the radiation situation, namely the content of cesium-137 in soil, water, as well as in animal products both in the North-Western region and in other subjects of the Russian Federation. Due care must be taken when organizing the feeding of productive animals (dairy cows, beef cattle in the final fattening period), whose products, without an additional processing stage, can be directed to consumption by the population.

Hematological leukocyte indices provide additional information about intoxication and the state of the immune response and become an alternative to determine a number of immuno-biochemical parameters. The aim of the work is to study the effect of the antioxidant mitophen on the leukocyte indices of blood that characterize the nonspecific reactivity of the organism of broiler chickens. The chickens of the I and III experimental groups were given mitophen daily from the daily age at the rate of 25 and 50 g/t of feed for a month, the II and IV-25 and 50 g/t of feed only in the first and third weeks of the experiment. The control group received the main diet without the drug. The leukocyte indices were determined mathematically by the leukogram. It was found that the use of mitophen significantly increases the index: of shift of blood leukocytes, of the ratio of eosinophils and lymphocytes, and lowers the index of the ratio of lymphocytes and eosinophils, which indicates the positive effect of the drug on the granulocytopoiesis and nonspecific resistance of broiler chickens. At the same time, the use of mitophen significantly reduces index: of immunoreactivity, of the ratio of lymphocytes to monocytes, and pseudoeosinophils to monocytes, which characterizes the positive effect of the antioxidant on monocytopoiesis and nonspecific cellular immunity of the bird body due to monocytes.