Phytosterols (PSs) are plant-originated steroids. Over 250 PSs have been isolated, and each plant species contains a characteristic phytosterol composition. A wide number of studies have reported remarkable pharmacological effects of PSs, acting as chemopreventive, anti-inflammatory, antioxidant, antidiabetic, and antiatherosclerotic agents. However, PS bioavailability is a key issue, as it can be influenced by several factors (type, source, processing, preparation, delivery method, food matrix, dose, time of administration into the body, and genetic factors), and the existence of a close relationship between their chemical structures (e.g., saturation degree and side-chain length) and low absorption rates has been stated. In this sense, the present review intends to provide in-depth data on PS therapeutic potential for human health, also emphasizing their preclinical effects and bioavailability-related issues.

Based on a systematic study of the key problems of development and standardization of internal audit in Russia, the article highlights the key factors of the need to develop internal audit in modern economic conditions and proves the need to introduce internal audit in the practice of economic activity of organizations. Based on the study of existing approaches to the standardization of internal audit, existing both in modern economic science and implemented in practice, they are critically analyzed in terms of classification and an author's chart of the organizational stages of development and approval of the organization's internal audit standards is proposed, which is universal for any organization subject to the conditions for developing internal audit standards, taking into account compliance with applicable laws Islands, audit efficiency and credibility.

Аннотация. Среди общего ряда современных металлических конструкций с использованием профильных труб (гнутосварных профилей) рассмотрены блоки покрытий и перекрытий из перекрестных ферм типа «Пятигорск» как наиболее перспективные решения. Из-за небольших размеров они условно классифицируются как «карманные» модули и изготавливаются цельносварными. Представлена перспективность применения профильных труб круглого и овального сечений для дальнейшей модернизации перекрестных ферм и других решетчатых конструкций. Показана вполне приемлемая корректность и простота оптимизационного расчета овальных сечений по приближенной методике. Описано новое техническое решение решетчатых конструкций, способствующее улучшению их технико-экономических характеристик. Выявлены снижение расхода конструкционного материала при реализации такого решения на примере стропильных ферм, а также повышение степени надежности и конструктивной безопасности зданий и сооружений за счет приближения решетчатых конструкций к их расчетным схемам (моделям) в виде шарнирно-стержневых систем. Ключевые слова: легкие металлические конструкции, замкнутые гнутосварные профили, перекрестные системы, оптимизация, расход конструкционного материала, круглые трубы, овальные трубы

The article deals with the issues related to the harmful effects on the human body of anti-nutritional components (anti-nutritional factors of natural origin) that can block active enzymes that break down protein compounds. A comparative analysis of anti-nartative components of protein-containing plant origin under the influence of thermal nature and parameters of electric-discharge treatment has been carried out

Laurel noble (sweet bay) leaves are widely used for food (aromatic seasoning, preservative) and medicinal (antibacterial, anti-inflammatory, hepatoprotective) purposes. The plant is actively cultivated and has many ecological forms. The main sesquiterpene lactones in laurel leaves are costunolide and dehydrocostuslactone. The content of these substances varies significantly depending on the ecological-geographical, climatic, edaphic and other factors. Several methods have been developed and used to quantify these sesquiterpene lactones in laurel leaves. They differ significantly in the cost of equipment and materials required for research, the duration of the analysis, economic costs, and the accuracy of the results. The article presents the results of studying the content of costunolide and dehydrocostuslactone in the leaves of some forms of sweet bay, cultivated on the southern coast of the Crimean Peninsula using capillary electrophoresis methods, reliably confirmed by the results of HPLC analysis of the leaves of the studied forms of sweet bay. Studies have shown that both methods give comparable results. At the same time, the HPLC method is characterized by a higher accuracy of results and a lower determination error, and the method of capillary electrophoresis allows a study to be carried out with lower economic costs using simpler methods. Both methods are pharmacopoeial and are recommended for the standardization of medicinal plant materials.