Presence of combined natural foci of plague, tularemia, Crimean-Congo hemorrhagic fever, West-Nile encephalitis, Astrakhan spotted fever in the North-West Precaspian region was substantiated. Influence of anthropogenic and climatic conditions in formation of combined natural foci of infectious diseases of bacterial, rickettsial and viral etiology was pointed out. Up-to-date potential epidemic danger of the territories under consideration was evaluated.

Based on the experience of the long-term epizootiologic survey in the natural foci of plague, determined were the principles of usage of the developed methodology of monitoring of the dangerous infectious diseases combined with plague. The methods of collection of the field material to identify the agents of different infections were suggested. Prospects of complex differentiation of territory according to the level of epidemic danger were considered. The tasks of further study of the areas, spatial and biocenotic structure of combined natural foci of plague and other dangerous infections were formulated.

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