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Dependence of the critical current on the misorientation angle in high-temperature superconductor (HTS) [001]-tilt bicrystal is theoretically examined. It’s argued that in the case of relatively small values of the bicrystal misorientation angle θ (θ ≤ 10–15°) the critical current as well as the resistive state emergence are determined by depinning of Abrikosov vortices, which are locked by c-oriented edge dislocations which form the low-angle [001]-tilt grain boundary and are aligned in a linear row along it. Dependence of the depinning critical current on the misorientation angle of bicrystal is calculated for this case and it reveals a good agreement with experimental data obtained on HTS bicrystals with low-angle [001]-tilt grain boundaries.