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Annot For finding-out of a role of separate groups of polyphenols in realization hepatoprotective properties of maksar we investigate activity of polyphenolic complexes (PPC) from duramen and cellular culture of maakia amur. Experiments are carried out on 40 not purebred white rats with an experimental СCl4-hepatites. Therapeutic efficiency of researched objects estimated on their influence on survival rate of animals, morphological and biochemical parameters of a liver and wheys of blood. In rat's CCl4-hepatitis PPC from duramen and cellular culture of maakia amur reduce the acute toxity of tetrachloromethane, decrease the necrosis of hepatocytes and cellural infiltration of liver's parenchyma, prevent from development of fatty and protein dystrophy of a liver, normalize the activity of amino transferase, ƒ-glutamyltransferase in blood, the concentration of proteins and lipids, stimulate conjugation of bilirubin. The therapeutic effect of PPC of cellular culture is more evident. The hepatoprotective action is caused by a presence of isoflavonoids daidzein, retuzin, genistein, afromozin, formononetin, orobol, tektorigenin, maakiain and medicarpin. PPC from a culture of cells doesn't influence on a level of cholesterol in blood, that apparently is caused by an absence of mono- and dimeric stilbenes in its structure.

Birch is a rich and widely occurring source of substances for medicinal preparations. The previous pharmacological investigation of tinctures from various parts of this plant showed, in particular, promising properties of birch bark extracts [1].The purpose of this work was to select an optimum extractant for birch bark, for which purpose we have used aqueous ethanol solutions of various concentrations. EXPERIMENTAL CHEMICAL PARTThe experiments were performed with dry birch bark extracts obtained using 20, 30, 35, 40, and 70% aqueous ethanol

Research is devoted to the problem of efficient use of the herbs of Salsola collina Pall. Studied and analyzed the known technological methods of processing and to obtain standardized extractive complexes. Had developed an effective method of obtaining the liquid extract. The parameters of the extraction process and the proposed complex extractant, allowing a high degree of depletion of plant material for the various groups of biologically active substances, and get the finished product with desired properties.