Peutz-Jeghers syndrome is a genetic disorder inherited in an autosomal dominant pattern and characterized by a mutation in the STK11 gene. According to domestic literature, the risk of inheriting this pathology from a parent to a child is 50%. According to WHO data, in 2018, more than 74,000 new cases of colorectal tumors were detected in the Russian Federation, with 5–10% of cases being hereditary syndromes, of which 1% is Peutz-Jeghers syndrome. The frequency of occurrence is approximately 1/29,000–1/120,000.  The aim of the work is to share the experience of diagnosing and treating a patient with Peutz-Jeghers syndrome. Today, we have the ability to timely diagnose pathological changes in the mucous membrane of the small intestine, perform minimally invasive treatment, reducing rehabilitation time due to a decrease in surgical trauma.

The aim of the study is to observe a patient with vascular malformation of the ileum complicated by recurrent bleeding. Materials and methods: the article presents a clinical case of small intestine bleeding from ileum angiectasia in a 64-year-old patient. At the patient's place of residence, a video capsule endoscopy of the gastrointestinal tract was performed, angiectasia of the ileum was detected, from which fresh blood was received. Upon admission, the patient has iron deficiency anemia, and hematocheesia. In our institution, the patient underwent diagnostic egophagogastroduodenoscopy, video colonoscopy, balloon-assisted enteroscopy (BAE). According to BAE, vascular malformation with a diameter of up to 10 mm is viuzalized in the ileum Results: The patient underwent endoscopic treatment: one endoclypse was applied to the identified vascular malformation. Conclusion: The capabilities of clinicians in the differential diagnosis of pathological conditions of the small intestine are enhanced by the availability of modern equipment in medical and preventive institutions, as well as to perform minimally invasive treatment, reducing the rehabilitation time due to the reduction of surgical trauma.

The aim of the study is to observe a patient with vascular malformation of the ileum complicated by recurrent bleeding. Materials and methods: the article presents a clinical case of small intestine bleeding from ileum angiectasia in a 64-year-old patient. At the patient's place of residence, a video capsule endoscopy of the gastrointestinal tract was performed, angiectasia of the ileum was detected, from which fresh blood was received. Upon admission, the patient has iron deficiency anemia, and hematocheesia. In our institution, the patient underwent diagnostic egophagogastroduodenoscopy, video colonoscopy, balloon-assisted enteroscopy (BAE). According to BAE, vascular malformation with a diameter of up to 10 mm is viuzalized in the ileum Results: The patient underwent endoscopic treatment: one endoclypse was applied to the identified vascular malformation. Conclusion: The capabilities of clinicians in the differential diagnosis of pathological conditions of the small intestine are enhanced by the availability of modern equipment in medical and preventive institutions, as well as to perform minimally invasive treatment, reducing the rehabilitation time due to the reduction of surgical trauma.

Purpose: to analyze the results of diagnosis and treatment of tumors of the small intestine, which served as a source of small bowel bleeding. Materials and methods: 35 patients were analyzed: men - 19 (59.4%), women - 16 (41.6%) aged 19 to 85 years, with tumors and tumor-like lesions of the jejunum and ileum. The main indication for examination of the small intestine in these patients was the search for a source of bleeding that was not identified by standard diagnostic methods (esophagogastroduodenoscopy and colonoscopy). After analyzing the clinical picture in 5 examined patients with identified tumors of the small intestine, 3 (15.5%) clinical symptoms were manifested by obvious intestinal bleeding characterized by melena or hematochezia, and in 2 (10.5%) patients the course was latent. Conclusion: After analyzing the results of the diagnosis of small intestine tumors complicated by bleeding in young and middle-aged patients, the survey data demonstrate the importance of enteroscopy techniques in patients with iron deficiency anemia and chronic recurrent bleeding