Research objective: to determine the risk factors for the spread of coronavirus infection among women of fertile age.Materials and methods. Authors analyzed the medical records (case histories and questionnaires) of 60 women of fertile age who were treated for coronavirus disease. After analysis of medical and social factors women were divided into age groups. Analysis of risk factors for coronavirus disease was determined by calculating the odds ratio according to Wald at p < 0.05.Results. Evaluation of the odds ratio of the COVID-19 chances depending on the nature of work of women of different ages showed that with intense work the risk of disease increases 2.5 times in the age group up to 30 years, which also confirms the analysis of previous indicators, that younger women with moderate workloads have more opportunities to attend mass events and crowds. In the structure of extragenital diseases in women with coronavirus disease, the chances of disease increased 2.6 times in those women who had a history of chronic tonsillitis. Among the history of infectious diseases, the chance ratio of coronavirus disease was increased in women over 30 years of age who had pertussis. Such data may indicate a similar mechanism of development of these diseases, because the causative agent of pertussis also penetrates the upper respiratory tract and may be accompanied by neurological symptoms – the appearance of seizures and bronchospasm.Conclusions. The data obtained in this way allow us to separate a narrower cohort of women of fertile age who may develop coronavirus disease. This will further allow developing proposals for a more efficient distribution of vaccines among the female population of Ukraine and reduce the prevalence of coronavirus infection.

Objectives: to identify clinical and ultrasound indicators that can determine the need for further examination of fertile aged women who smoke and have metabolic syndrome (MS) regarding the risk of developing somatic pathology or diseases of the reproductive system.Materials and methods. 2 groups of women of fertile age were examined: the first group consisted of 20 women who smoked with MS, the second group included 20 women who smoked without MS. All women were interviewed using a specially designed general and reproductive health questionnaire. Ultrasound examination of the abdominal cavity and pelvic organs was performed using convex and transvaginal sensors according to existing examination protocols.Results. Women of the first group had a higher body mass index and other obesity parameters, which is typical for MS. Women of the second group smoked more cigarettes per day. The identified early onset of menstrual function in women with MS may be a manifestation of hormonal homeostasis disorders at the end of puberty with a predominance of estradiol secretion and insufficient progesterone synthesis in the second phase of the menstrual cycle. A significant amount of blood loss during menstruation and painful menstruation in women of the first group may be a manifestation of adenomyosis, which confirms by echo-positive and echo-negative inclusions in the myometrium and thickening of the uterine walls. In most patients with MS ultrasound showed multifollicular ovaries, which may point at polycystic ovary syndrome, given changes in body mass index and ovarian structure as a response on hyperestrogenemia. Prolonged manifestation of MS also negatively affected the abdominal organs, as evidenced by echo-positive inclusions in the liver and pancreas parenchyma, which is a manifestation of inflammatory diseases of these organs.Conclusions. The combination of prolonged smoking and metabolic syndrome leads to more pronounced changes in the reproductive system and abdominal organs, which in turn expands the range of recommended methods of instrumental examination for such women.