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Academy, 95 Gor'kogo Str., Blagoveshchensk, 675000, Russian Federation 2 Amur Regional Clinical Hospital, 26 Voronkova Str., Blagoveshchensk, 675028, Russian Federation The article presents the literary overview dedicated to the diaphragmatic hernias. As an example, a case of the traumatic diaphragmatic hernia with the clinical picture of the pleurisy was described. The thoracoabdominal knife injury of the diaphragm was the feasible reason of this hernia. In this case, a long asymptomatic course of the disease with some gastroenterological symptoms was the reason for the early diagnostics not to be performed. Firstly, the patient was hospitalized to the pulmonology department because of the pleurisylike clinical picture of his case. A diaphragmatic hernia was found only after examination of the patient. A laparoscopic operation failed and the patient was successfully treated by the surgery.

The problem of the thromboembolism of the pulmonary artery (TEPA) is still not solved and quite urgent especially for patients with malignant tumors. The risk of TEPA at this patients' rank is about 10-40% and 10% with lethal outcome without adequate prophylaxis. The TEPA prophylaxis is based on the stratification of the risk level that is subsequently depends on quality and quantity of the risk factors for every case personally.

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The purpose of the study is to propose a method of preoperative correction of the symptoms of endogenous intoxication syndrome and associated respiratory disorders in patients with colorectal cancer. The study involved 68 patients having a surgery for colorectal cancer of different localization, with an increased leukocyte index of intoxication by V.K.Ostrovsky in preoperative period. The first group patients (37 subjects) in the preoperative preparation program took Cytoflavin® according to the developed scheme. The second group patients (31 subjects) had a standard preoperative preparation. As result of the research, there was revealed a positive effect of the proposed method of preoperative preparation on hematological parameters of endogenous intoxication (decrease in values of the parameters of Calf-Caliph, Ostrovsky and integral index of intoxication) and parameters of oxygen status, which changes indicated a decrease in tissue hypoxia (decrease in tissue oxygen consumption). The positive effect of the proposed method of preoperative preparation was observed in the postoperative period (reduced severity of respiratory disorders and hematological symptoms of endogenous intoxication).