A modern person sedentary lifestyle has become very common. There is substantial number of office employees in megapolises. However, sedentary work causes health risks for many employees associated with many diseases. Health problems, associated with musculoskeletal apparatus, ophtalmological, gastrointestinal disesases, varicosity, hemorrhoids are often associated with office work. The objective of the article is to review occupational diseases and common drugs for treatment sedentary lifestyle modern office manager various diseases.

Lactofiltrum is a combination drug, pharmacological action of which is associated with the properties of its active components, namely lignin and lactulose. The effects of Lactofiltrum include normalization of the colon microbiota, decrease in the intensity of endogenous toxic conditions, and possibility of using it in patients of different age (the drug is recommended for adults and children >1 year of age); these properties of Lactofiltrum explain its popularity among doctors of various specialties and patients. Objective. To analyze the binary activity of Lactofiltrum using the methods of qualitative and quantitative assessment of the adsorption and prebiotic actions. Materials and methods. Microphotographs of the morphology and surface texture of Lactofiltrum were obtained using the OlympusBX-51 optical microscope. The following methods were proposed for qualitative and quantitative assessment of the adsorption and prebiotic actions of Lactofiltrum: method of ‘visual qualitative assessment of the enterosorbent adsorption activity’ and reverse complexometric titration. Prebiotic activity was evaluated using microbiological methods. Conclusion. Our experimental study confirmed high adsorption and prebiotic activity of Lactofiltrum. Key words: adsorption and prebiotic activity, Lactofiltrum, microbiocenosis, drug for children older than 1 year of age

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