The presented article focuses on the relationship between social exclusion and the transport geographical characteristics which are considered as instrumental in the development of social exclusion, and also as a negative feature that can even deepen the exclusion. In the first part, the author generally defines and examines the concept of social exclusion as a selectively operating process of differentiation, the way it has been perceived over time and its individual aspects with an emphasis on the spatial dimension. The second part of the article is devoted to the conditional relationship between transportation and social exclusion. Besides the description of this process of exclusion, which is transport related, there is a discussion of the role of transport (in)accessibility and characteristics of personal mobility as a crucial factors which cause or intensify the exclusion. On the other hand it also offers a chance to reintegrate individuals into society.