Solitary fibrous tumour is a rare spindle cell neoplasm. It was first described by Klemper and Rabin in 1931. Initially it was assumed that these tumours .The tumour originates from mesenchyme. The diagnosis is confirmed by immunohistochemical confirmation for CD 34. These tumours usually have good prognosis. These tumours are treated with surgical excision with close followup. Local recurrences were seen after incomplete surgical excision
Several studies are going on to study the effects of transfusing stored RBCs on recipients. Several biochemical changes occur in stored blood, which may have some medical effects on the recipients. The biochemical changes may vary from donar to donar as well as from Blood bank to Blood bank. Also effects of transfused RBCs will vary from recipient to recipient. Lot of clinical trial should be taken before assessing the safety of stored RBCs.
OBJECTIVESTo study the various biochemical changes occurring in a stored whole blood.
MATERIAL AND METHODSAnalysis of biochemical changes occurring in stored whole blood in 20 voluntary donars was done in a Blood bank of a Tertiary Hospital.
RESULTSOf the 6 biochemical parameters studied, only significant changes were seen in potassium and albumin after storage. There was a significant decrease in albumin concentration and steady increase in potassium values.
CONCLUSIONCertain biochemical changes do occur in stored whole blood over a duration of storage. As the demand for blood is high due to various medical conditions, the treating consultant should be aware of the biochemical changes seen in stored whole blood.
Aim and objective:The objective of this study was to correlate laboratory tests during the evolution of dengue fever, comparing frequencies between the different clinical forms in order to use test results to predict the severity of the disease. Methods: This is an observational, descriptive and retrospective study of 50 patients with clinical and serological diagnoses of dengue fever. The tests analyzed were blood count, platelet count, and serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) concentrations. Results: Thrombocytopenia and elevated transaminases were observed in patients with classic dengue fever. The main laboratory abnormalities found in dengue hemorrhagic fever were thrombocytopenia, hemoconcentration and elevated transaminases, similar to severe dengue with the exception of hemoconcentration. Most laboratory abnormalities started on the 3rd day but were more evident on the 5th day with restoration of values by the 11 th day; this was more prominent in under 15-year-olds and with the more severe clinical forms. Conclusion: These results are relevant in assessing the disease because they can be used as markers for more severe forms and can help by enabling the adaptation of the therapeutic conduct to the needs of individual patients.
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