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Background: Intestinal infection in the post-transplant period is a common source of morbidity and mortality. Diarrhea with or without abdominal pain, bloating, nausea and vomiting constitute the most common symptomology which guides the clinician towards appropriate treatment, but what happens when the clues are few? Case Presentation: We report a case of recent renal allograft recipient who presented with severe abdominal pain without diarrhea or fever. After undergoing various tests, the diagnosis was finally clinched by jejunal biopsy since, it is supported by stool polymerase chain reaction. Conclusions: This case highlights a common organism like giardia can have a varied presentation. This case mimicking almost as an acute abdomen while can present with a diagnostic challenge.