Colesevelam possesses antidiabetic properties, which could potentiate sulphonylurea or insulin‐induced hypoglycemia; clinically significant hypoglycemia, as a side effect to bile acid sequestrants, may be under‐recognized in clinical practice.

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Spinal cord injury‐induced hyponatremia is an under‐recognized entity, without a mention in the European hyponatremia guidelines. We present a case of a 56‐year‐old female quadraplegic patient with cervical cord injury, presenting with severe hyponatremia and tonic–clonic seizures. This case highlights the challenges in medical management; action mechanisms are further discussed.

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