Our goal was to create an original knowledge-based intelligent software application for control and monitoring of drinking wate distribution system implemented and experimented for three cities from Jiu Valley region. For this purpose we created an knowledge-based intelligent systems for control and monitoring the parameters referring to the raw water catchment stations and the measuring instruments as: water turbidity, valves' state, the flow on the loading tank', the drinking water level in the tanks and the pressure at the customers The knowledge-based intelligent control and monitoring system was implemented in the Visual Basic programming language which is a high productivity development environment, a visual development software, object orientated, ideal for this type of applications, processes simulations control and monitoring.