Tuberculosis (TB) disease affects a large population worldwide but is often missed. Early diagnosis can be challenging at times due to failure to include TB in the differential diagnoses. Tuberculosis is a treatable disease but it can lead to undesirable consequences if left untreated. Here we report a case of a young Guatemalan woman presented with respiratory failure and extensive lung opacification on imaging who went into cardiac arrest. Post resuscitation, workup was significant for Mycobacterium tuberculosis (TB) on sputum smear. Despite appropriate treatment, she expired. The aim of this paper is to summarize TB complications that directly contribute to mortality as many clinicians do not consider TB as an immediate cause of death.