The major objective focusses on synthesizing silver nanoparticles (Ag-NPs) from Solanum virginianum under optimum conditions. In this study, mathematical tools such as central composite design (CCD) and artificial neural networking (ANN) used for identifying process optimizing parameters. The maximum wavelength recorded (λ=425 nm) using chemical mediated synthesis for the leaf extract. Based on the results, that plant extract concentration (15 g ml
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