The present study demonstrates the presence of a chronic inflammation status in young women with PCO. These parameters are mainly related to obesity and, to a lesser extent, to IR.

High FSH concentrations, but not oestradiol, are positively associated with bone mass loss in both skeletal regions, in patients with spontaneous POF.

We found that these patients did not show high levels of depression, but they did show high values of anxiety. Psychosocial stress was higher throughout the year before they lost their menstrual cycles, than during the year before the psychological evaluation. Regarding personality profiles, the following scales stood out from the rest: Actively Modifying, Self-Indulging, Internally Focused, Realistic/Sensing, Feeling-Guided, Dominant/Controlling and Dissatisfied/Complaining.