In this study, brain damage caused by cerebral malaria was induced by parasitized erythrocyte rupture and sequestration, which led to inflammation and blood vessel damage. Therefore, this research objective to determine the effect of oxygen administration on the histopathological features and sequestration of CD3 lymphocyte T cells on Plasmodium berghei ANKA/PbA-infected vascular endothelial brain tissue of mice. The study samples consisted of 39 C57BL/6 mice, which were divided into 3 groups: G1 contained normal mice; G2 contained PbA-infected mice; G3 were mice infected with PbA, and administered HBO 2.4 ATA for 10 days straight. Histopathological examination of the of brain tissue and CD3 lymphocyte T cell expression was carried out using immuno-histochemical at the end of the study. Therefore, the results of this study indicate that HBO administration can reduce the level of parasites, can improve the histopathological features of the brain, and can reduce the sequestration of CD3 cells in the brain's blood vessels. According to the results, it can be concluded that 10 sessions of HBO 2.4 ATA exposure can reduce the level of parasites, enhance the histopathological features of brain tissue and decrease the sequestration of CD3 lymphocyte T cells.

This vaginal inflammation was observed to decrease with a decrease in PMN. 2,14,15 Neutrophils do not always play a protective role, as uncontrolled influx of neutrophils in the vagina provokes and amplifies pathogenic inflammation. 10,16,17 Damage to the vaginal epithelium occurs by a series of mechanisms as above as well as other factors such as hyphae elongation and the simultaneous release of fungal peptide toxin secretion (Candidalysin). 18,19 Most women with RVVC (71%) require long-term antifungal treatment as maintenance therapy to