Brain metastasis is rare occurrence with metastatic prostate cancer whereas bones, lung, pleura are the most common organs to be involved. During our cadaver dissection, it was found that the patient had a subdural hematoma secondary to brain metastasis as a result of metastatic prostate cancer. The case report presents with the dissection of Brain showing clear cut midline shift and Obliteration of anterior and posterior horn of ventricles. The symptoms in brain metastasis may not occur initially but may appear in late involvement. SubDural hematoma is of common occurrence in andropause age group especially who are receiving anti-coagulants or had minor head injury. The incidence of brain metastases may be increasing due to better imaging techniques. In such patients, use of anti-coagulants, anti-platelets or anti-VEGF therapy can increase the risk of intracranial hemorrhage hence used with caution.
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