AIMTo assess the correlation of HBA1C levels with left ventricular diastolic dysfunction in newly diagnosed Type 2 diabetic patient. This prospective study was done at Department of General Medicine, OPD, Medical Wards, Stanley Medical College and Hospital, Chennai. RESULTThe mean HBA1C levels were meaningfully more in Left Ventricular Diastolic Dysfunction (LVDD) positive group compared to the LVDD negative group by 1.33%. This significant difference of 15% increase in mean HBA1C levels in LVDD positive group compared to the LVDD negative group is true and has not occurred by chance. CONCLUSIONOne-fifth to one-third of diabetic patients will develop LVDD. Patients with HBA1C (8 to 10) have double the chances to develop LVDD than with HbA1c 6.5 to 8. Patients with HBA1C more than 10 have five times the chances to develop LVDD than with HbA1C 6.5 to 8. Patients with HBA1C more than 10 have three times the chances to develop LVDD than with HBA1C 8 to 10. One-fourth to one-half of diabetic patients will develop LVDD grade 1. Patients with HBA1C 8 to 10 have double the chances to develop LVDD grade 1 than with HBA1C 6.5 to 8. Patients with HBA1C more than 10 have four times the chances to develop LVDD grade 1 than with HBA1C 6.5 to 8. Patients with HBA1C more than 10 have two times the chances to develop LVDD than with HBA1C 8 to 10. KEYWORDSType 2 Diabetes, Left Ventricular Diastolic Dysfunction, HbA1C. HOW TO CITE THIS ARTICLE:Perumal V, Narayanan N, Rangarajan J, et al. A study to correlate HbA1C levels and left ventricular diastolic dysfunction in newly diagnosed type II diabetes mellitus.

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BACKGROUNDCopper Sulphate ingestion is a relatively common method of committing suicide in South India. It can be life-threatening with high mortality due to its deleterious effects on upper GIT, kidney, liver and blood.

BACKGROUND CEA (carcinoembryonic antigen) is mainly associated with malignant conditions, but there is a modest increase in non-malignant conditions such as aging, and atherosclerosis and this study is to find correlation of CEA levels in stroke patients. MATERIALS AND METHODS A case control study conducted from March 2016 to August 2016 in Stanley Medical College, General Medicine Department. RESULTS The mean CEA levels were significantly elevated in infarct group compared to control group by a mean difference of 5.09 ng/mL (73% higher), which is significant with p value of 0.0001, likewise the mean CEA levels were significantly elevated in haemorrhage group compared to control group by a mean difference of 3.26 ng/mL (64% higher). The CEA levels were significantly elevated in infarct group compared to haemorrhage group by a mean difference of 1.83 ng/mL (26% higher). This difference is significant with a p-value of 0.0071. CONCLUSION The CEA levels are higher among stroke patients than normal population. The elevation is more among ischaemic stroke patients than haemorrhagic stroke patients. Infarct stroke patients had 3.73 times carcinoembryonic antigen levels compared to healthy subjects, haemorrhage stroke patients had 2.75 times carcinoembryonic antigen levels compared to healthy subjects and infarct stroke patients had 1.36 times carcinoembryonic antigen levels compared to haemorrhage stroke patients.