The agri-food sector contributes significantly to economic and social advancements globally despite numerous challenges such as food safety and security, demand and supply gaps, product quality, traceability, etc. Digital technologies offer effective and sustainable ways to these challenges through reduced human interference and improved data-accuracy. Innovations led by digital transformations in the agri-food supply chains (AFSCs) are the main aim of ‘Agri-Food 4.0’. This brings significant transformations in the agri-food sector by reducing food wastage, real-time product monitoring, reducing scalability issues, etc. This paper presents a systematic review of the innovations in the agri-food for digital technologies such as internet-of-things, artificial intelligence, big data, RFID, robotics, block-chain technology, etc. The employment of these technologies from the ‘farm to fork’ along AFSC emphasizes a review of 159 articles solicited from different sources. This paper also highlights digitization in developing smart, sensible, and sustainable agri-food supply chain systems.