Diastolic and systolic myocardial dysfunction in patients with type 2 diabetes may be identified by quantitative tissue Doppler imaging before the onset of clinical signs of heart failure and before the appearance of traditional echocardiographic indices of systolic myocardial dysfunction.

Aims/hypothesis Using modern echocardiography, we quantified the extent of global myocardial function and

summary Background: ST-segment changes and QRS prolongation are electrocardiographic (ECG) markers of myocardial ischemiaHypothesis: This study was undertaken to investigate the appearance of QRS duration changes with or without concomitant ST-segment changes during atypical anginal episode.Methods: For this purpose, 126 patients underwent 12-lead surface ECG and signal-averaged electrocardiogram