No abstract

Herein, we describe a mild and convenient protocol for Michael addition of nitroalkanes to 3‐methyl‐4‐nitro‐5‐styrylisoxazoles using neat “water extract of rice straw ash (WERSA)” as a catalyst and medium at room temperature. Method developed is simple to operate and yields range from good to excellent. This eco‐friendly protocol also successfully used for the synthesis of pharmaceutical interest, such as γ‐nitrobutyricacid an intermediate for the preparation of Baclofen.

ZnO nanoparticles (ZnO NPs) catalyzed synthesis of novel 4H‐chromene hemiacetals with 3‐methyl‐2‐pyrazolin‐5‐one and cyclic 1,3‐diketone with high regioselectivity in aqueous medium has been demonstrated. This method is applicable to diverse substituted chromene hemiacetals and different functionalized 1,3‐diketones. All these reactions proceeded smoothly, and the products were obtained in good to excellent yields. The catalyst could be recycled and reused up to 5 cycles without any loss of efficiency.

No abstract

No abstract