An efficient synthesis of bisphenols is described by condensation of substituted phenols with corresponding cyclic ketones in presence of cetyltrimethylammonium chloride and 3-mercaptopropionic acid as a catalyst in extremely high purity and yields.

A series of new oxopyrimidine were prepared by cyclocondensation route with various substituted chalcones in presence of alcoholic solution of potassium hydroxide at reflux temperature. The synthesized oxopyrimidine derivatives were characterized by means of their IR,1H NMR, mass spectral data and elemental analysis. The synthesized oxopyrimidines derivatives were evaluated for antibacterial and antifungal activities, some of them were found to possess significant activity.

Quinoxaline derivatives have been synthesized in high to excellent yields in the presence of thiamine hydrochloride (VB 1) as an inexpensive, non-toxic and metal ion free catalyst at ambient temperature.

Temperature. -(PAWAR*, O. B.; CHAVAN, F. R.; SURYAWANSHI, V. S.; SHINDE, V. S.; SHINDE, N. S.; J. Chem. Sci. (Bangalore, India) 125 (2013) 1, 159-163, http://dx.doi.org/10.1007/s12039-012-0345-y ; Dep. Chem., Shri Chhatrapati Shivaji Coll., Omerga 413 606, India; Eng.) -C. Cyrus 24-162

Derivatives of substituted Benzimidazole were prepared by condensation of o-phenylene diamine and substituted carboxylic acid in presence of zink diacetate as oxidant (1a-1e). These on nitration yields (2a-2e), further on treatment with 2-amino 4-phenyl 1, 3 thiazole in presence of Nafion-H affords corresponding Mannich bases (3a-3e). Last step reaction involves one pot, three component Mannich reactions of benzimidazole, formaldehyde and heterocyclic amines are efficiently catalyzed by heterogeneous Nafion-H at ambient temperature to give the mannich bases in good to excellent yields. The catalyst can be easily recovered and reused without any decrease of activity for at least five times.